The Rat Model Market is expanding with the increase in R&D activities in pharmaceutical industries. Continuous support in the form of investments and grants, and personalized medicine fueling the demand for personalized humanized rat models are some of the factors driving the growth of the Market.
These rat models are being used in many applications such as toxicology, oncology, diabetes, neurology, immunology and infectious diseases, and others (rare disease, cardiovascular, metabolic disease, hematopoiesis, and regenerative medicines).
Rat Model Market Based on Type;
The market is categorized into an outbred rat, inbred rats, knockout/genetically modified rats, conditioned/surgically modified rats, hybrid/congenic rats, and immunodeficient rats. the outbred rat’s segment is estimated to account for the largest share of the global Rat Model Market. However, the knockout/genetically modified rat segment is expected to be the fastest-growing segment owing to the use of this type of rat models to carry out researches on disease such as oncology, obesity, heart disease, diabetes, arthritis, drug abuse, anxiety, aging, and Parkinson’s disease.
Toxicology is the study of adverse effects of chemical, physical, or biological agents on people, animals, and the environment. Rats are predominantly used in the toxicity and safety assessment studies of a drug substance. Other animals that are used in these studies include mice, rabbits, and guinea pigs. Toxicology testing in animals is required to prove that the new drugs are safe before their administration in humans. A high proportion of new drugs fail in the preclinical stage is due to the unacceptable toxicity in animals.
Global Rat Model Market, By Therapeutic Area
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Rat models serve as suitable animal models for detailed and accurate analysis of the mechanism of human neurodegenerative diseases. They help in the development and evaluation of new therapeutic strategies. Transgenic rat models are available for several neurological human conditions such as prion diseases, human retroviral diseases,
Alzheimer’s disease, Parkinson’s disease, motor neuron diseases, anxiety, and others. Rat models for anxiety disorder have been useful for providing information on the brain and behavioral mechanisms involved in the etiology and physiopathology of anxiety disorder.
The key players in the global Rat Model Market include Charles River Laboratories International (US), Envigo (UK), and Taconic Biosciences (US). Other players include Horizon Discovery Group (UK), genOway (France), Laboratory Corporation of America Holdings (US), Transposagen Biopharmaceuticals (US), Transviragen (US), Janvier Labs (France), and Biomere (US).
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